Bookcover of The Development of iron chelators for the treatment of cancer
Booktitle:
The Development of iron chelators for the treatment of cancer
Aroylhydrazone and thiosemicarbazone chelators for cancer treatment
LAP LAMBERT Academic Publishing
(2009-05-19
)
eligible for voucher
ISBN-13:
978-3-8383-0139-6
ISBN-10:
3838301390
EAN:
9783838301396
Book language:
English
Blurb/Shorttext:
This monograph describes the development of novel NT and DpT series aroylhydrazone and thiosemicarbazone iron chelators for the treatment of cancer. It neatly reviews the role of iron in cancer and the development of chelators for cancer treatment before describing the synthesis and biological activity of the NT and DpT series of chelators in both in-vitro and in-vivo models of cancer. The authors conclude that the DpT series, in particular, may be clinical potential in the treatment of cancer.