Bookcover of Advance Research Method for Diabetes Mellitus
Booktitle:

Advance Research Method for Diabetes Mellitus

Floating Drug Delivery Systems Mucoadhesive Systems

LAP LAMBERT Academic Publishing (2013-11-01 )

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ISBN-13:

978-3-659-48106-2

ISBN-10:
3659481068
EAN:
9783659481062
Book language:
English
Blurb/Shorttext:
Diabetes is one of the major causes of death and disability in the world. The global figure ofpeople with diabetes is set to rise from the current estimate of 150 million to 220 million in 2010 and 300 million in 2025. Most cases will be of type II diabetes, with a sedentary lifestyle and obesi. A plethora of antidiabetic drugs are used in clinic, of which metformin hydrochloride is a very widely used and accepted drug. In spite of its favorable clinical response and lack of significant drawbacks, chronic therapy with metformin hydrochloride suffers from certain specific problems of which, the most prominent being the high dose, short biological half life low bioavailability and high incidence of gastrointestinal side effects (30% cases) Also the main site of its absorption is reported to be proximal small intestines Thus, the development of controlled-release dosage forms in form of gastro-retentive system would clearly be advantageous.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Laxmi Banjare
Number of pages:
124
Published at:
2013-11-01
Stock:
Available
Category:
Pharmacy
Price:
54.90 €
Keywords:
Diabetes mellitus, Advance research method, gastro-retentive drug delivery, metformin

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