Обложка Development of Compression Coated Colon Targeted 5-Fluorouracil Tablet
Название книги:

Development of Compression Coated Colon Targeted 5-Fluorouracil Tablet

Development and Characterization of Compression Coated Colon Targeted Tablet of 5-Fluorouracil

LAP LAMBERT Academic Publishing (2012-08-20 )

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ISBN-13:

978-3-659-22194-1

ISBN-10:
3659221945
EAN:
9783659221941
Язык Книги:
Английский
Краткое описание:
The purpose of this study was to develop and evaluate a drug delivery system in vitro based on a compression coated tablet containing 5-fluorouracil (5-FU) in core and pectin Hydroxypropyl Methylcellulose (HPMC) mixture in coat layer. The main reason for selecting pectin was its biodegradation in colon by colonic flora. On other hand, high molecular weight HPMC increases mechanical strength of tablet coat around a drug core during its transportation in gastro-intestinal tract. Multiple regression analysis with two way ANOVA revealed that both factors had statistically significant influence for the response studied (P<0.05). Results of Tukey test showed the relative contribution of each level of different factors for the response studied.
Издательский Дом:
LAP LAMBERT Academic Publishing
Веб-сайт:
https://www.lap-publishing.com/
By (author) :
Mukesh Patel, Kanu Patel, Natvarlal Patel
Количество страниц:
112
Опубликовано:
2012-08-20
Акции:
В наличии
Категория:
Фармацевтика
Цена:
49.00 €
Ключевые слова:
Factorial Design, Pectin, Hydroxypropyl methylcellulose, 5-Fluorouracil

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