Sequential Model
Enzyme catalysis, Protein subunit, MWC model
978-613-9-12864-8
6139128641
80
2012-01-07
34,00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The sequential model (also known as the KNF model ) is a theory that describes co-operativity of protein subunits.This model suggests that the subunits of multimeric proteins have two conformational states. The binding of the ligand causes conformational change. Although the subunits go through conformational changes independently (as opposed to in the MWC model) the switch of one subunit makes the other subunits more likely to change, by reducing the energy needed for subsequent subunits to undergo the same conformational change.
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