Copertina di Evaluation of New Lupane-Type Triterpene 'Diospyrosonate'
Titolo del libro:

Evaluation of New Lupane-Type Triterpene 'Diospyrosonate'

as Anti-Inflammatory Principle from Diospyros malabarica Bark Extract

LAP LAMBERT Academic Publishing (26.01.2011 )

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ISBN-13:

978-3-8443-0104-5

ISBN-10:
3844301046
EAN:
9783844301045
Lingua del libro:
Inglese
Risvolto di copertina:
A novel lupane-type triterpene 'Diospyrosonate' (P1) has been isolated from anti-inflammatory activity guided fractionation of petroleum ether extract precipitate of Diospyros malabarica stem bark with a gradient of ethyl acetate in petroleum ether. Further P1 was screened for anti- inflammatory activity on carrageenan and dextran induced inflammation model in rats at the dose level of 50 mg/kg body weight. Treatment of inflammed rats with P1 has showed significant reduction in inflammation caused by carrageenan (P<0.05) and dextran (P<0.01). Hence P1 can be considered as the principle component responsible for the anti-inflammatory activity for Diospyros malabarica bark.The characterization of P1 was done by spectral studies like IR, 1H-NMR, 13C-NMR & mass spectroscopy. On the basis of spectral studies the structure of P1 has been elucidated as Betulin esterified at C-29 with a C-14 acid. This is a novel triterpenoid isolated from the bark of D. malabarica for the first time and given a trival name Diospyrosonate.
Casa editrice:
LAP LAMBERT Academic Publishing
Sito Web:
https://www.lap-publishing.com/
Da (autore):
VICHITRA KAUSHIK, Versha Parcha, Ratan Lal Khosa
Numero di pagine:
84
Pubblicato il:
26.01.2011
Giacenza di magazzino:
Disponibile
categoria:
Farmacia
Prezzo:
49,00 €
Parole chiave:
"Lupane, Triterpenoid, Anti-Inflammatory, Phytopharmacology.", anti-inflammatory, Lupane, Phytopharmacology.

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