- Scienze naturali, medicina, informatica, tecnica
- Medicina
- Farmacia
- Evaluation of New Lupane-Type Triterpene 'Diospyrosonate'
- Copertina di Evaluation of New Lupane-Type Triterpene 'Diospyrosonate'
- Titolo del libro:
-
Evaluation of New Lupane-Type Triterpene 'Diospyrosonate'
as Anti-Inflammatory Principle from Diospyros malabarica Bark Extract
LAP LAMBERT Academic Publishing (26.01.2011 )
eleggibile a buono
- ISBN-13:
978-3-8443-0104-5
- ISBN-10:
- 3844301046
- EAN:
- 9783844301045
- Lingua del libro:
- Risvolto di copertina:
- A novel lupane-type triterpene 'Diospyrosonate' (P1) has been isolated from anti-inflammatory activity guided fractionation of petroleum ether extract precipitate of Diospyros malabarica stem bark with a gradient of ethyl acetate in petroleum ether. Further P1 was screened for anti- inflammatory activity on carrageenan and dextran induced inflammation model in rats at the dose level of 50 mg/kg body weight. Treatment of inflammed rats with P1 has showed significant reduction in inflammation caused by carrageenan (P<0.05) and dextran (P<0.01). Hence P1 can be considered as the principle component responsible for the anti-inflammatory activity for Diospyros malabarica bark.The characterization of P1 was done by spectral studies like IR, 1H-NMR, 13C-NMR & mass spectroscopy. On the basis of spectral studies the structure of P1 has been elucidated as Betulin esterified at C-29 with a C-14 acid. This is a novel triterpenoid isolated from the bark of D. malabarica for the first time and given a trival name Diospyrosonate.
- Casa editrice:
- LAP LAMBERT Academic Publishing
- Sito Web:
- https://www.lap-publishing.com/
- Da (autore):
- VICHITRA KAUSHIK, Versha Parcha, Ratan Lal Khosa
- Numero di pagine:
- 84
- Pubblicato il:
- 26.01.2011
- Giacenza di magazzino:
- Disponibile
- categoria:
- Farmacia
- Prezzo:
- 49,00 €
- Parole chiave:
- "Lupane, Triterpenoid, Anti-Inflammatory, Phytopharmacology.", anti-inflammatory, Lupane, Phytopharmacology.
