Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. TOMSO, or 2-methoxy-4--5-methylamphetamine, is a lesser-known and a substituted amphetamine. TOMSO was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the dosage range is listed as 100–150 mg, and the duration listed as 10–16 hours. TOMSO is inactive on its own; it is activated with the consumption of alcohol. It produces intense time distortion and a threshold. Shulgin gives it a +++ on the Shulgin Rating Scale. Very little data exists about the pharmacological properties, metabolism, and toxicity of TOMSO.