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Könyv címe:

Homology Modeling of Human NK-1 Receptor and Docking Study

Structure Based Drug Design

LAP LAMBERT Academic Publishing (16.11.2015 )

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ISBN-13:

978-3-659-80420-5

ISBN-10:
3659804207
EAN:
9783659804205
Könyv nyelve:
angol
Ismertető:
Neurokinin-1 (NK-1) receptor regulates many biological functions related to cancer, such as tumor cell proliferation, angiogenesis and migration of tumor cells for invasion and metastasis. The NK-1 receptor antagonists specifically inhibit tumor cell proliferation, migration of the tumor cells and show antiangiogenic effect. Therefore, the development of NK-1 antagonists for the treatment of cancer is of current interest. The 3D structure of NK-1 is not available from protein data bank. This hampers the design of selective NK-1 antagonists. This book describes the homology modeling of the human NK-1 receptor using multiple templates to provide structural basis for the design of new NK-1 inhibitors and anticancer agents. The authors anticipate that the book will be very useful for the researchers who are working on the design and development of NK-1 receptor antagonists and anticancer agents.
Kiadó:
LAP LAMBERT Academic Publishing
Weboldal:
https://www.lap-publishing.com/
Szerezte:
Manish K. Gupta, Viney Kumar
Oldalszám:
92
Kiadja:
16.11.2015
Raktárkészlet:
Raktáron
Kategória:
Gyógyszerészet
Ár:
54,90 €
Kulcsszavak:
Cancer, Docking, Drug design, homology modeling, NK-1 receptor, Tachykinin

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