Bookcover of Recent Approaches for Enhancing the Solubility of Drugs
Booktitle:

Recent Approaches for Enhancing the Solubility of Drugs

For increasing the Potency of drugs

LAP LAMBERT Academic Publishing (2017-07-28 )

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ISBN-13:

978-3-659-46465-2

ISBN-10:
3659464651
EAN:
9783659464652
Book language:
English
Blurb/Shorttext:
Solubility is the phenomenon of dissolution of solid in liquid phase to give a homogenous system. Solubility is one of the important parameter to achieve desired concentration of drug in systemic circulation for pharmacological response to be shown. It is generally recognized that poor solubility is one of the most frequently encountered difficulties in the field of pharmaceutics. Low solubility and subsequent unsatisfactory dissolution rate are often compromise with the oral bioavailability of drugs. This article demonstrates the various techniques which are used to enhance the aqueous solubility which can thus be a valuable aid to increase the efficiency and reducing side effect for the drugs. Hence, various techniques are used for the improvement of the solubility of poor water soluble drugs which include Hydrotropy, pH adjustment, Cosolvency, Misceller solubilization, Supercritical fluid techniques, Solid dispersion, Complexation, Microemulsion, use of surfectants and Nanonization.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Dushyant Kumar Dewangan
Number of pages:
76
Published on:
2017-07-28
Stock:
Available
Category:
Pharmacy
Price:
23.90 €
Keywords:
Bioavailibility, Dissolution, solid dispersion, solubility Enhancement, drug absorption

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