Bookcover of Polydnavirus Histone H4 and its role in insect immunity
Booktitle:

Polydnavirus Histone H4 and its role in insect immunity

Polydnavirus Histone H4

LAP LAMBERT Academic Publishing (2012-09-19 )

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ISBN-13:

978-3-659-24398-1

ISBN-10:
3659243981
EAN:
9783659243981
Book language:
English
Blurb/Shorttext:
Cotesia plutellae (Braconidae: Hymenoptera) is a solitary endoparasitoid wasp that parasitizes the diamondback moth, Plutella xylostella (L.) (Yponomeutidae: Lepidoptera). For successful parasitization, its symbiotic polydnavirus (CpBV) helps the wasps to attenuate host immune capacity and manipulate host developmental physiology. An analysis of CpBV genome sequence indicated the presence of one putative gene (CpBV-H4) showing a high similarity to histone H4. Histone H4, one of the four histone subunits along with H2A, H2B and H3, forms an eukaryotic nucleosome core. Along with H3, it plays a central role in nucleosome formation. CpBV-H4 showed expression in different tissues in parasitized P. xylostella. Transient expression of CpBV-H4 in nonparasitized P. xylostella resulted in significant impairment of hemocyte-spreading and decreased gene expression of host H4, while knock-down of the transient expression using double-stranded RNA interference recovered the immune capacity and gene expression.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Wael Gad, Yonggyun Kim
Number of pages:
88
Published on:
2012-09-19
Stock:
Available
Category:
Biology
Price:
49.00 €
Keywords:
Cotesia plutellae; Plutella xylostella; Endoparasitoid; Polydnavirus; Histone H4; Expression; Nucleosome; Chromosome remodeling

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