Bookcover of Paclitaxel
Booktitle:

Paclitaxel

Betascript Publishing (2010-07-16 )

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ISBN-13:

978-613-0-91190-4

ISBN-10:
6130911904
EAN:
9786130911904
Book language:
English
Blurb/Shorttext:
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific Yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'TAXOL'. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent. A newer formulation, in which paclitaxel is bound to albumin, is sold under the trademark Abraxane. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is also used for the prevention of restenosis.
Publishing house:
Betascript Publishing
Website:
https://www.betascript-publishing.com/
Edited by:
Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
Number of pages:
68
Published on:
2010-07-16
Stock:
Available
Category:
Medicine
Price:
45.82 S$
Keywords:
chemotherapy, National Cancer Institute, Research Triangle Institute

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