Bookcover of Myelogram in macrophage activation syndrome
Booktitle:

Myelogram in macrophage activation syndrome

Search for new predictive criteria for the diagnosis of secondary MAS in adults

Our Knowledge Publishing (2021-05-12 )

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ISBN-13:

978-620-3-68573-2

ISBN-10:
6203685739
EAN:
9786203685732
Book language:
English
Blurb/Shorttext:
The image of hemophagocytosis is neither specific nor constant during macrophagic activation syndrome (MAS).The objective of our study was to search for new cytological criteria to optimize the diagnostic orientation.We have, thus, conducted a prospective evaluative monocentric study. Cases of suspected adult MAS presented to the hematology department of CHU la Rabta between June 2017 and January 2019, in order to perform a myelogram were included. Thirty five bone marrow smears were examined at diagnosis. A second reading of the bone marrow smears was performed in a blinded fashion to estimate the number of macrophages/1000 nucleated elements, the intensity of hemophagocytosis, the nature of the phagocytic elements as well as the presence of images of multiple phagocytosis were specified. The study revealed that none of these cytological parameters studied was predictive of the diagnosis. However, guidelines for myelogram reading in patients with suspected MAS have yet to be defined.
Publishing house:
Our Knowledge Publishing
Website:
https://sciencia-scripts.com
By (author) :
Aya Chakroun, Intissar Helali
Number of pages:
72
Published on:
2021-05-12
Stock:
Available
Category:
Specialized Medical occupations
Price:
39.90 €
Keywords:
Macrophagic activation syndrome, myelogram

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