Folate Receptor 1
978-613-6-43960-0
6136439603
80
2011-07-19
34.00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Folate receptor alpha is a protein that in humans is encoded by the FOLR1 gene.The protein encoded by this gene is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells.This gene is composed of 7 exons; exons 1 through 4 encode the 5' UTR and exons 4 through 7 encode the open reading frame. Due to the presence of 2 promoters, multiple transcription start sites, and alternative splicing of exons, several transcript variants are derived from this gene. These variants differ in the lengths of 5' and 3' UTR, but they encode an identical amino acid sequence.
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