Bookcover of Evaluation of New Pentamethoxy Flavonol 'Cordiofolinol'
Booktitle:

Evaluation of New Pentamethoxy Flavonol 'Cordiofolinol'

as Anti-Inflammatory Principle from Haldina cordifolia Bark Extract

LAP LAMBERT Academic Publishing (2011-08-18 )

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ISBN-13:

978-3-8443-8730-8

ISBN-10:
3844387307
EAN:
9783844387308
Book language:
English
Blurb/Shorttext:
A novel Pentamethoxy Flavonol 'Cordiofolinol' (P3) has been isolated from anti-inflammatory activity guided fractionation of methanol extract of Haldina cordifolia stem Bark with a gradient of methanol in chloroform. Further P3 was screened for anti-inflammatory activity on carrageenan and dextran induced inflammation model in rats at the dose level of 50 mg/kg body weight. Treatment of inflammed rats with P3 has showed significant reduction in inflammation caused by carrageenan (P>0.01) and dextran (P>0.05). Hence P3 can be considered as the principle component responsable for the anti-inflammatory activity for Haldina cordifolia bark. The characterization of P3 was done by spectral studies like IR, 1H-NMR, 13C-NMR & mass spectroscopy. On the basis of spectral studies the structure of P3 has been elucidated as 5, 7, 3', 4', 5' –Pentamethoxy Flavonol. This is a novel Flavonol isolated from the bark of H. cordifolia for the first time and given a trival name Cordiofolinol.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
VICHITRA KAUSHIK, Ratan Lal Khosa, Versha Parcha
Number of pages:
84
Published on:
2011-08-18
Stock:
Available
Category:
Pharmacy
Price:
49.00 €
Keywords:
Carrageenan, Dextran, Haldina cordifolia, UV, IR, NMR, Flavonol, Anti-Inflammatory, Mass, Flavonole, anti-inflammatory, Massivholzplatte

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