Bookcover of Evaluation of Antiulcer Activity of the Leaf of Osyris quadripartita
Booktitle:

Evaluation of Antiulcer Activity of the Leaf of Osyris quadripartita

LAP LAMBERT Academic Publishing (2016-12-19 )

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ISBN-13:

978-3-330-02508-0

ISBN-10:
3330025085
EAN:
9783330025080
Book language:
English
Blurb/Shorttext:
Objective: To evaluate the antiulcer activity of the leaf extract of Osyris Quadripartita ( OQ) in albino wistar rats. Methods: The 80% methanolic extract of OQ leaves was subjected to acute toxicity test and phythochemical analysis. The extract’s anti-ulcer activity were studied using the pylorus ligation and ethanol induced ulcer model both for dose dependent (100, 200, 400mg/kg) and time dependent (200mg/kg for 10 & 20 days) studies. Volume, pH, total acidity, ulcer score and ulcer index were determined for pylorus ligation induced ulcer model and ranitidine 50mg/kg (R50) was used as a standard dug. In ethanol induced ulcer model ulcer score and ulcer index were determined and sucralfate 100mg/kg (S100) was used as a standard drug. Conclusion: The 80% methanolic extract of OQ exhibited anti-ulcer activity which is comparable to the standard drugs and this could be attributed to the possible presence of one or more secondary metabolites. This supports the ethnomedicinal use of leaves of Osyris quadripartita.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Bharat Mishra, Mastewal Abebaw, Badmanaban Ramalingam
Number of pages:
104
Published on:
2016-12-19
Stock:
Available
Category:
Pharmacy
Price:
49.90 €
Keywords:
Ethnomedicinal, Osyris quadripartita, pylorus ligation, Anti-ulcer activity

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