Dam (Methylase)
Methylase, Enzyme, Methyl group, Adenine, DNA, DNA replication, DNA mismatch repair, DNA polymerase III holoenzyme
978-620-0-01647-8
620001647X
84
2013-01-10
34.00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. DAM methylase (DNA adenine methylase) is an enzyme that adds a methyl group to the adenine of the sequence 5'-GATC-3' in newly synthesized DNA. Immediately after DNA synthesis, the daughter strand remains unmethylated for a short time. When DNA polymerase makes an error resulting in a mismatched base-pair or a small insertion or deletion during DNA synthesis, the cell will repair the DNA by a pathway called mismatch repair. However, the cell must be able to differentiate between the template strand and the newly synthesized strand.
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