Biodegradable in Situ Microparticles for Sustained
Protein Delivery
Stability of a Model Protein during Incorporation
and Release from Biodegradable in Situ Forming Drug
Delivery Systems
978-3-639-07659-2
3639076591
332
2011-09-02
79.00 €
eng
https://images.our-assets.com/cover/230x230/9783639076592.jpg
https://images.our-assets.com/fullcover/230x230/9783639076592.jpg
https://images.our-assets.com/cover/2000x/9783639076592.jpg
https://images.our-assets.com/fullcover/2000x/9783639076592.jpg
The objective of this work was to evaluate the
suitability of in situ forming biodegradable
microparticles for the controlled delivery of
proteins. Particular goals were: a) to evaluate the
flexibility of the release patterns of in situ
implant and in situ microparticle formulations using
hen egg white lysozyme as model protein; b) to
characterize, if and how the integrity of the model
protein is affected by formulation ingredients, the
manufacturing process, storage of the ISM and the
release from the formulations; c) to optimize
protein delivery from in situ forming implant and
microparticle systems, with regard to shape and
completeness of the release; d) to find / validate
reliable methods allowing to extract and thus to
characterize the model protein in biodegradable in
situ formulations.
https://morebooks.de/books/gb/published_by/vdm-verlag-dr-mueller/3/products
Organic chemistry
https://morebooks.de/store/gb/book/biodegradable-in-situ-microparticles-for-sustainedprotein-delivery/isbn/978-3-639-07659-2