Bookcover of Benzimidazole-2-carboxylic acids
Booktitle:

Benzimidazole-2-carboxylic acids

Chemistry, Pharmacology and QSAR

LAP LAMBERT Academic Publishing (2010-10-31 )

Books loader

Omni badge eligible for voucher
ISBN-13:

978-3-8433-7236-7

ISBN-10:
3843372365
EAN:
9783843372367
Book language:
English
Blurb/Shorttext:
Rheumatoid arthritis is progressive, autoimmune inflammatory chronic disorder which do not have curative treatment yet. Aryl and hetero-aryl acids has maximum share of anti-inflammatory drugs in the therapeutics today as non steroidal anti-inflammatory drugs (NSAIDs). Benzimidazole moiety with heteroaryl and psudoacedic nature is promising moiety for development of NSAIDs. In the present project, synthesis, pharmacological evaluation, probable mechanism of action and quantitative structure-activity relationship (QSAR) of benzmidazole-2-carboxylic acids are reported. The excellent efficacy and safety was observed for benzimidaxole-2-carboxylic acid derivatives in laboratory animal models of inflammation and rheumatoid arthritis without side-effect of gastrointestinal disturbances. The reliving effects against pain and fever in experimental animal models suggested promise as potential NSAID.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Prasad Thakurdesai, S.G. Wadodkar, C.T. Chopde
Number of pages:
124
Published on:
2010-10-31
Stock:
Available
Category:
Pharmacy
Price:
94.99 S$
Keywords:
pharmacology, Rhumatoid Arthritis, Benzimidazole, Anti-Inflammatory, Analgesic, Antipyretic, Synthesis, QSAR, In vivo, In vitro, Mechanism of action, Pharmacology, anti-inflammatory, analgesics, antipyretic, In Vitro

Books loader

Newsletter

Adyen::cup Adyen::unionpay Paypal CryptoWallet Wire Transfer

  0 products in the shopping cart
Edit cart
Loading frontend
LOADING