Bookcover of AL-34662
Booktitle:

AL-34662

Alphascript Publishing (2010-09-28 )

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ISBN-13:

978-613-2-84636-5

ISBN-10:
6132846360
EAN:
9786132846365
Book language:
English
Blurb/Shorttext:
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. AL-34662 is an indazole derivative drug that is being developed for the treatment of glaucoma. It acts as a selective 5-HT2A receptor agonist, the same target as that of hallucinogenic drugs like psilocin, but unlike these drugs, AL-34662 was designed specifically as a peripherally selective drug, which does not cross the blood-brain barrier. This means that AL-34662 can exploit a useful side effect of the hallucinogenic 5-HT2A agonists, namely reduction in intra-ocular pressure and hence relief from the symptoms of glaucoma, but without causing the hallucinogenic effects that make centrally active 5-HT2A agonists unsuitable for clinical use. In animal studies, AL-34662 has been shown to be potent and effective in the treatment of symptoms of glaucoma, with minimal side effects.
Publishing house:
Alphascript Publishing
Website:
https://www.alphascript-publishing.com/
Edited by:
Frederic P. Miller, Agnes F. Vandome, John McBrewster
Number of pages:
68
Published on:
2010-09-28
Stock:
Available
Category:
Pharmacy
Price:
29.00 €
Keywords:
glaucoma, 5-HT2A, Receptor, Agonist, Psilocin, intraocular

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