Couverture de Study Of Diclofenac Sodium 12H From Acrylic Polymer Coating Materials
Titre du livre:

Study Of Diclofenac Sodium 12H From Acrylic Polymer Coating Materials

Formulation Development Through Pelletization Technique

LAP LAMBERT Academic Publishing (28-09-2011 )

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ISBN-13:

978-3-8465-1545-7

ISBN-10:
3846515450
EAN:
9783846515457
Langue du livre:
Anglais
texte du rabat:
The present study is to investigate the effect of Ammonio Methacrylate Copolymer Type B (Eudragit RS 30 D) on the release kinetics study of diclofenac sodium form coated pellets. Eudragit RS 30 D and xanthan gum was added into the formulation at 5:1 ratio. Different percent of this polymeric combination was loaded on to the drug-loaded pellets. It was found that the cumulative % release of drug decreased with the increase of polymer load in all cases. Better sustaining effect was found from Eudragit RS 30 D and xanthan gum combinations. Drug was released linearly along with time throughout the whole dissolution process in phosphate buffer (pH 6.8) and it was also revealed that, in all cases the release of diclofenac sodium followed mixed release kinetics but zero order release kinetics predominates.
Maison d'édition:
LAP LAMBERT Academic Publishing
Site Web:
https://www.lap-publishing.com/
de (auteur) :
Madhabi Lata Shuma, Shimul Halder, Abul Kalam Lutful Kabir
Numéro de pages:
120
Publié le:
28-09-2011
Stock:
Disponible
Catégorie:
Pharmacie
Prix:
49.00 €
Mots-clés:
sustained release, In vitro, kinetic analysis., diclofenac sodium, Pellets, In Vitro, kinetic analysis, Diclofenac sodium

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