Couverture de Some 4-Thiazolidinones as Antimicrobial Agents
Titre du livre:

Some 4-Thiazolidinones as Antimicrobial Agents

4-Thiazolidinones: Antimicrobial Agents

LAP LAMBERT Academic Publishing (20-11-2017 )

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ISBN-13:

978-3-659-68637-5

ISBN-10:
3659686379
EAN:
9783659686375
Langue du livre:
Anglais
texte du rabat:
4-Thiazolidinones are derivatives of thiazolidine with a carbonyl group at the 4-position, substitutents in the 2-, 3-, and 5-positions may be varied, but greatest differences in structure and properties is exerted by the group attached to the carbon atom in 2-position. Syntheses of 4-thiazolidinones are three component reactions involving an amine, a carbonyl compound and a mercaptoacetic acid.The process can be one pot condensation reaction. The reaction has been suggested to proceed via imine formation followed by attack of sulfur nucleophile on imine carbon. The last step involves intramolecular cyclization with the elimination of water to give 4-thiazolidinone. These derivatives are known to exhibit diverse biological activities like anticonvulsant, antidiarrheal, anti-platelet, antihistaminic, antimicrobial, antiviral, antidiabetic, anti-inflammatory, analgesic etc.
Maison d'édition:
LAP LAMBERT Academic Publishing
Site Web:
https://www.lap-publishing.com/
de (auteur) :
Om Prakash Agrawal, Pankaj Kumar Sonar, Shailendra K. Saraf
Numéro de pages:
72
Publié le:
20-11-2017
Stock:
Disponible
Catégorie:
Pharmacie
Prix:
35.90 €
Mots-clés:
Antimicrobial Agents, isatin, 4-Thiazolidinone, Thiosemicarbazone

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