Effect of crowdedness in the life cycle of Lysenin studied by HS-AFM
978-3-639-56048-0
3639560485
128
2017-05-09
49.90 €
eng
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Lysenin life cycle start with a soluble monomer that binds to membrane lipid sphingomyelin. After an oligomerization process Lysenin nonamers, known as prepores, suffer endocitosis. In the late endosome the acidic conditions induce the oligomer insertion, resulting in the so-call pore state. High-Speed Atomic Force Microscopy allow to study Lysenin life cycle, highlighting the crucial role of crowdedness in it.
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La bioquímica, la biofísica
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