Synthesis of Some Novel Bioactive Indoles as Anticancer Agents的封面
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Synthesis of Some Novel Bioactive Indoles as Anticancer Agents

Bioactive Indoles

LAP LAMBERT Academic Publishing (2020-03-26 )

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ISBN-13:

978-620-2-51660-0

ISBN-10:
6202516607
EAN:
9786202516600
书籍语言:
英文
作品简介:
The original work consists of two projects: In the first project: 5-(Aryldiazenyl)-thiazoles and 1,3,4-thiadiazoles bearing indole were synthesized via reaction of hydrazonoyl halides and indole-thiosemicarbazone and alkyl (indolyl)carbodithioate, respectively. In the second project: 3-Acetylindole proved to be a useful precursor for the synthesis of various 1,3-thiazoles, 1,3,4-thiadiazoles and pyrido[3,2-e][1,2,4] triazolo[4,3-a]pyrimidin-5(7H)-one. Fifteen of the new compounds have been evaluated for their antitumor activity against the human breast carcinoma cell line. The results indicated that many of the tested compounds showed moderate to high anticancer activity.
出版社 :
LAP LAMBERT Academic Publishing
网址:
https://www.lap-publishing.com/
由(作者):
Sobhi Gomha, Abdou O. Abdelhamid, Sahar Kandeel
页码 :
116
发表日期:
2020-03-26
现货:
备有现货
类别:
有机化学
价格:
54.90 €
关键词:
3-Acetylindole, 1, 3, 4-thiadiazoles, 3-thiazoles, pyrazoles; coupling reactions; thiosemicarbazides; hydrazonoyl halides, anti-cancer activity.

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