Study of Ondansetron with SSRI's in Some Animal Models of Depression的封面
书籍主题:

Study of Ondansetron with SSRI's in Some Animal Models of Depression

The antiemetic and additive antidepressant activity of ondansetron with SSRI's

LAP LAMBERT Academic Publishing (2012-04-30 )

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ISBN-13:

978-3-659-00163-5

ISBN-10:
3659001635
EAN:
9783659001635
书籍语言:
英文
作品简介:
By the year 2020, depression will be the second leading cause of death. So it should be treated carefully. Classically, Tricyclic antidepressants and Monoamine oxidase Inhibitors were used to treat depression. But recently, clinically effective antidepressants with rapid onset of action and less side effects are developed. Here, selective serotonin reuptake inhibitors like fluoxetine, escitalopram are used in combination with ondansetron.Ondansetron may directly block 5HT3 receptors which modulate neuronal release of other neurotransmitters like Nor-epinephrine which is the possible mechanism of action. And also SSRI’s are having gastrointestinal side effects which can be inhibited by ondansetron & also show additive antidepressant effect. In present study, an attempt was made to find out which is the best combination for antidepressant treatment between different doses of ondansetron and SSRI’s.
出版社 :
LAP LAMBERT Academic Publishing
网址:
https://www.lap-publishing.com/
由(作者):
Anuradha Chivate, Niranjan Chivate
页码 :
112
发表日期:
2012-04-30
现货:
备有现货
类别:
药学
价格:
49.00 €
关键词:
Serotonin, antidepressant, SSRI, Ondansetron, Antiemetic, Locomotor, TST, MAO-A, FST

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