Copper Complexes - Vol II的封面
书籍主题:

Copper Complexes - Vol II

Synthesis, Characterization and Biological Evaluation of NNS donor schiff base molecular adducts of Copper (II) Chloride

LAP LAMBERT Academic Publishing (2016-05-05 )

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ISBN-13:

978-3-659-88057-5

ISBN-10:
3659880574
EAN:
9783659880575
书籍语言:
英文
作品简介:
NNS Schiff base molecular adducts belong to a group of thiourea derivatives and the biological activities of which are a function of the parent aldehyde or ketone are the most important properties of thiosemicarbazone class of ligands (hydrazine carbothioamindes). Their metal complexes, especially those containing copper (II) and iron (III) are more active than uncoordinated NNS Schiff base molecular adducts and enhanced biological activity of metal thiosemicarbazones has been under investigation for some time. NNS Schiff base molecular adducts are very good ligands and it has been shown that their biological activity is related to their ability to coordinate to metal centres in enzymes. NNS Schiff base molecular adducts are more active in cell destruction, as well as in the inhibition of DNA synthesis. NNS Schiff base molecular adducts are obtained by condensation of thiosemicarbazide or a substituted thiosemicarbazide at the N (4) position with a suitable aldehyde or ketone.
出版社 :
LAP LAMBERT Academic Publishing
网址:
https://www.lap-publishing.com/
由(作者):
Richa Kothari
页码 :
76
发表日期:
2016-05-05
现货:
备有现货
类别:
药学
价格:
39.90 €
关键词:
Cancer, Chemical synthesis, Cytotoxicity, medicinal chemistry, copper complex

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